Product Information

Abacavir EP Impurity E

Catalogue number	ABC-011
Product Name	Abacavir EP Impurity E
Sub Category	Pharma Reference Standard; Pharmaceutical/API Drug Impurities/Metabolites
API	Abacavir
CAS Number	208762-35-0
Alternate CAS Number	No Data Available
HS Code	29339900
Molecular formula	C14H20N6O
Molecular Weight	288.35
Synonyms	(1R,3S)-3-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopentanemethanol
Appearance	Off-White Solid
Melting Point	>80°C
Storage	-20°C Freezer
Solubility	Methanol (Slightly), Water (Slightly)
Stability	No Data Available
Boiling Point	No Data Available
Applications	(1R,3S)-3-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopentanemethanol (Abacavir EP Impurity E) is an impurity of Abacavir (A104990). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Information	This product is for commercial use only and strictly NOT for human or animal consumption
Shipping Condition	Cold condition shipping. (Ice Pack)
Inventory Status	In Stock
Quantity
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