Product Information

Abacavir EP Impurity C

Abacavir EP Impurity C
Catalogue number ABC-001
Product Name Abacavir EP Impurity C
Sub Category Pharma Reference Standard; Pharmaceutical/API Drug Impurities/Metabolites
API Abacavir
CAS Number 124752-25-6
HS Code 29339900
Molecular formula C₁₁H₁₄N₆O
Molecular Weight 246.27
Synonyms Abacavir USP Related Compound A(Abacavir Descyclopropyl impurity)
Appearance Off-White to Pale Yellow Solid
Melting Point 177°C
Storage -20°C Freezer
Solubility DMSO (Slightly), Methanol (Slightly, Heated)
Stability No Data Available
Boiling Point No Data Available
Applications Descyclopropyl Abacavir (Abacavir EP Impurity C; Abacavir Related Compound A) is an intermediate of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Information This product is for commercial use only and strictly NOT for human or animal consumption
Shipping Condition Stable to be shipped at room temperature
Inventory Status In Stock
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Chemical Name: Abacavir EP Impurity C

Synonym: Abacavir USP Related Compound A(Abacavir Descyclopropyl impurity)

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