Product Information

Abacavir INT

Catalogue number	ABC-004
Product Name	Abacavir INT
Sub Category	Pharma Reference Standard; Pharmaceutical/API Drug Impurities/Metabolites
API	Abacavir
CAS Number	171887-03-9
Alternate CAS Number	No Data Available
HS Code	29339900
Molecular formula	C₅H₄Cl₂N₄O
Molecular Weight	207.02
Synonyms	N-(2-Amino-4,6-dichloropyrimidin-5-yl)formamide; Abacavir - In House Impurity; Abacavir Impurities
Appearance	Off-White to Pale Beige Solid
Melting Point	251°C
Storage	Amber Vial, Refrigerator, Under inert atmosphere
Solubility	DMSO, Methanol
Stability	No Data Available
Boiling Point	No Data Available
Applications	N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide (Abacavir - In House Impurity) is an intermediate of Abacavir (A105000). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Information	This product is for commercial use only and strictly NOT for human or animal consumption
Shipping Condition	Stable to be shipped at room temperature
Inventory Status	In Stock
Quantity
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