Product Information

Abacavir Enantiomer Impurity

Catalogue number	ABC-005
Product Name	Abacavir Enantiomer Impurity
Sub Category	Pharma Reference Standard; Pharmaceutical/API Drug Impurities/Metabolites
API	Abacavir
CAS Number	136470-79-6
Alternate CAS Number	No Data Available
HS Code	29339900
Molecular formula	C14H18N6O
Molecular Weight	286.30
Synonyms	(1R,4S)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol;(1R-cis)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (1R,4S)-Abacavir; Abacavir EP Impurity A; Abacavir Impurities; Ent-Abacavir
Appearance	Off-White to Pale Yellow Solid
Melting Point	>77°C
Storage	Refrigerator
Solubility	DMSO (Slightly), Methanol (Slightly)
Stability	No Data Available
Boiling Point	No Data Available
Applications	ent-Abacavir (Abacavir EP Impurity A) is an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Information	This product is for commercial use only and strictly NOT for human or animal consumption
Shipping Condition	Stable to be shipped at room temperature
Inventory Status	In Stock
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Product Overview Technical Data

Chemical Name: Abacavir Enantiomer Impurity

Synonym: (1R,4S)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol;(1R-cis)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (1R,4S)-Abacavir; Abacavir EP Impurity A; Abacavir Impurities; Ent-Abacavir