Product Information

Afatinib N-Oxide

Catalogue number	AFI-016
Product Name	Afatinib N-Oxide
Sub Category	Pharma Reference Standard; Pharmaceutical/API Drug Impurities/Metabolites
API	Afatinib
CAS Number	2413212-11-8
HS Code	29339900
Molecular formula	C24H25ClFN5O4
Molecular Weight	501.9 g/mol
Synonyms	(S,E)-4-((4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-N,N-dimethyl-4-oxobut-2-en-1-amine oxide; 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethyloxidoamino)-, (2E); (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethyloxidoamino)-2-butenamide
Chemical Name	(S,E)-4-((4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-N,N-dimethyl-4-oxobut-2-en-1-amine oxide
Appearance	Pale yellow to light brown crystalline solid
Storage	2-8°C in desiccator
Applications	The product can be used as reference standard.
Information	Afatinib N-Oxide is supplied with detailed characterization data compliant with regulatory guideline. Afatinib N-Oxide can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Afatinib.
Shipping Condition	Ambient
Inventory Status	Please Enquire
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Product Overview Technical Data

Chemical Name: Afatinib N-Oxide

Synonym: (S,E)-4-((4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-N,N-dimethyl-4-oxobut-2-en-1-amine oxide; 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethyloxidoamino)-, (2E); (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethyloxidoamino)-2-butenamide