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Sacubitril-(2R,4R)-Isomer

Sacubitril-(2R,4R)-Isomer
Catalogue number SAC-005
Product Name Sacubitril-(2R,4R)-Isomer
Sub Category Pharma Reference Standard; Pharmaceutical/API Drug Impurities/Metabolites
API Sacubitril
CAS Number 2259708-00-2
Alternate CAS Number 766480-48-2 (relative stereochemisrty)
HS Code 29339900
Molecular formula C24H29NO5
Molecular Weight 411.5
Synonyms (2R,4R)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic Acid Ethyl Ester; 4-(((2R,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic Acid;(R*,R*)-γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid α-Ethyl Ester; (αR,γR)-rel-γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid 4-Ethyl Ester; Sacubitril-(2R,4R) Isomer;
Chemical Name 4-(((2R,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid
Appearance Light Yellow Thick Liquid
Storage 2-8 °C for long term storage
Solubility ACN:H2O (8:2)
Stability Stable with Storage conditions as recomended
Applications (2R,4R)-Sacubitril is an impurity of Sacubitril, which is an antihypertensive drug used in combination with valsartan
Information Standards; Pharmaceutical/API Drug Impurities/Metabolites;
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Chemical Name: Sacubitril-(2R,4R)-Isomer

Synonym: (2R,4R)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic Acid Ethyl Ester; 4-(((2R,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic Acid;(R*,R*)-γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid α-Ethyl Ester; (αR,γR)-rel-γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid 4-Ethyl Ester; Sacubitril-(2R,4R) Isomer;

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