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Monomethyl Auristatin E

Monomethyl Auristatin E
Catalogue number AUS-006
Product Name Monomethyl Auristatin E
Sub Category Pharma Reference Standard; Pharmaceutical/API Drug Impurities/Metabolites
API Auristatin
CAS Number 474645-27-7
Alternate CAS Number 1359995-63-3 (HCl salt) ; 1400190-76-2 (TFA salt)
HS Code 29339900
Molecular formula C39H67N5O7
Molecular Weight 718.0 g/mol
Synonyms Vedotin; Brentuximab vedotin; (S)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-Hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamide
Chemical Name (2S)-N-[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-meth
Appearance White To Off-White
Melting Point >90°C (dec.)
Storage 2°C to 8°C
Solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
Stability No Data Available
Boiling Point No Data Available
Applications Monomethyl Auristatin E is supplied with detailed characterization data compliant with regulatory guideline. Monomethyl Auristatin E can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Auristatin.
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Chemical Name: Monomethyl Auristatin E

Synonym: Vedotin; Brentuximab vedotin; (S)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-Hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamide

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