Product Information

Ruxolitinib Phosphate IH Impurity-E

Catalogue number	RXL-004
Product Name	Ruxolitinib Phosphate IH Impurity-E
Sub Category	Pharma Reference Standard; Pharmaceutical/API Drug Impurities/Metabolites
API	Ruxolitinib
CAS Number	941685-37-6
HS Code	29339900
Molecular formula	C17H18N6
Molecular Weight	306.37 g/mol
Synonyms	(βS)-β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile; (3S)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile
Chemical Name	(3S)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile
Appearance	Off white to pale brown Solid
Storage	2-8°C Refrigerator
Solubility	Sparingly soluble in DMSO
Applications	(3S)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile is a newly developed JAK2 inhibitor therapy aimed to improve MPN-associated splenomegaly and systemic symptoms. The opposite enantiomer of Ruxolitinib.
Shipping Condition	Stable to be Shipped at room temperature.
Sample COA Purity	NLT 97.41 % by HPLC
Inventory Status	Under Development
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Product Overview Technical Data

Chemical Name: Ruxolitinib Phosphate IH Impurity-E

Synonym: (βS)-β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile; (3S)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile