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N-Methyl Pemetrexed

N-Methyl Pemetrexed
Catalogue number PMT-005
Product Name N-Methyl Pemetrexed
Sub Category Pharma Reference Standard; Pharmaceutical/API Drug Impurities/Metabolites
API Pemetrexed
CAS Number 869791-42-4
Alternate CAS Number 2243918-27-4 (Na salt)
HS Code 29420090
Molecular formula C21 H23 N5 O6
Molecular Weight 441.44
Synonyms L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-1-methyl-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, N-[4-[2-(2-Amino-4,7-dihydro-1-methyl-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, N-Methyl Pemetrexed, N-Methylpemetrexed, (2S)-2-[[4-[2-(2-Amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid, Pemetrexed Disodium Heptahydrate Imp. A (EP)
Appearance White to Pale Purple Solid
Storage 4°C, Hygroscopic
Solubility Aqueous Base (Slightly), DMSO (Slightly), Water (Slightly)
Stability Hygroscopic
Applications Pemetrexed EP Impurity A is chemically (2S)-2-[4-[2-(2-Amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzamido]pentanedioic acid (as per EP); {4-[2-(2-Amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-l-glutamic acid (as per USP). It is also known as N-Methyl Pemetrexed (USP). Pemetrexed EP Impurity A is supplied with detailed characterization data compliant with regulatory guideline.
Information NaaRini products are for analytical purpose only and not for human use.
Shipping Condition Under Cool Pack for Short term 2-3 days
Description Specific Rotation Report Result +12.5° (c = 0.5, 0.1N NaOH)
Inventory Status In Stock
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Chemical Name: N-Methyl Pemetrexed

Synonym: L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-1-methyl-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, N-[4-[2-(2-Amino-4,7-dihydro-1-methyl-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, N-Methyl Pemetrexed, N-Methylpemetrexed, (2S)-2-[[4-[2-(2-Amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid, Pemetrexed Disodium Heptahydrate Imp. A (EP)

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