Product Information

Nicotine Nitroso Impurity 1

Catalogue number	NIO-465
Product Name	Nicotine Nitroso Impurity 1
Sub Category	Pharma Reference Standard; Pharmaceutical/API Drug Impurities/Metabolites
API	Nitroso compounds
CAS Number	64091-91-4
HS Code	29339900
Molecular formula	C10H13N3O2
Molecular Weight	207.2
Synonyms	N-methyl-N-(4-oxo-4-(pyridin-3-yl)butyl)nitrous amide
Appearance	Colourless Solution
Storage	Keep container tightly closed in a dry and well-ventilated place
Solubility	Methanol (Soluble)
Stability	Light Sensitive
Applications	General Uses: Nicotine Testing, Environmental Monitoring and testing of nicotine biomarkers. Description: The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is a powerful lung carcinogen in animal models at a dose of 25mg/kg body weight (1) . NNK is considered “carcinogenic to humans” by the International Agency for Research on Cancer (2). NNK induce carcinogenesis by causing DNA adductions and mutations as well as promoting tumor growth through receptor-mediated effects (3). Nicotine can undergo chemical conversions into carcinogenic NNK during the process of curing & smoking (4). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
Shipping Condition	Stable to be shipped at room temperature
Inventory Status	In Stock
Quantity
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