Product Information

Etelcalcetide hydrochloride ( Synthetic)

Etelcalcetide hydrochloride ( Synthetic)
Catalogue number ETC-001
Product Name Etelcalcetide hydrochloride ( Synthetic)
Sub Category Pharma Reference Standard; Pharmaceutical/API Drug Impurities/Metabolites
API Etelcalcetide
CAS Number 1334237-71-6
Alternate CAS Number 1262780-97-1 (free base)
HS Code 29339900
Molecular formula C38H74ClN21O10S2
Molecular Weight 1084.72
Synonyms N-Acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl-D-argininamide disulfide with L-cysteine hydrochloride; AMG 416; AMG-416; AMG416; KAI-4169; KAI4169; KAI 4169 HCl; Etelcalcetide HCl.
Appearance Solid powder
Melting Point No Data Available
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years)
Solubility Soluble in DMSO, not in water
Stability No Data Available
Boiling Point No Data Available
Applications Etelcalcetide is a Calcium-sensing receptor agonist as a D-amino peptide calcimimetic for the treatment of secondary hyperparathyroidism. It can bind to and activate the CaSR (calcium-sensing receptor) in the parathyroid gland as an allosteric activator, resulting in PTH reduction and suppression. Amgen Inc. announced its submission of a New Drug Application to the FDA for etelcalcetide in Aug 2015.
Information This product is for commercial use only and strictly NOT for human or animal consumption
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Chemical Name: Etelcalcetide hydrochloride ( Synthetic)

Synonym: N-Acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl-D-argininamide disulfide with L-cysteine hydrochloride; AMG 416; AMG-416; AMG416; KAI-4169; KAI4169; KAI 4169 HCl; Etelcalcetide HCl.

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