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Clarithromycin EP Impurity F

Clarithromycin EP Impurity F
Catalogue number CLR-005
Product Name Clarithromycin EP Impurity F
Sub Category Pharma Reference Standard; Pharmaceutical/API Drug Impurities/Metabolites
API Clarithromycin
CAS Number 128940-83-0
HS Code 29339900
Molecular formula C₃₉H₇₁NO₁₃
Molecular Weight 761.98
Synonyms 12-O-Methyl Clarithromycin; 6,12-Di-O-methylerythromycin; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12-hydroxy-4-(((2R,4R,5S,6R)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7,13-dimethoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione; 6,12-Di-O-methylerythromycin A (USP)
Chemical Name (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12-hydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-
Appearance White to Light Beige Solid
Melting Point >116°C (dec.)
Storage -20°C
Solubility Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
Applications 12-O-Methyl Clarithromycin (Clarithromycin EP Impurity F) is a methylated impurity of the semi-synthetic macrolide antibiotic Clarithromycin (C559750). 12-O-Methyl Clarithromycin was shown to inhibit uptake of Clarithromycin into the lung cells.
Shipping Condition Stable to be shipped at room temperature
Sample COA Purity NLT 98 % By HPLC
Inventory Status Under Development
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Chemical Name: Clarithromycin EP Impurity F

Synonym: 12-O-Methyl Clarithromycin; 6,12-Di-O-methylerythromycin; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12-hydroxy-4-(((2R,4R,5S,6R)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7,13-dimethoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione; 6,12-Di-O-methylerythromycin A (USP)

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